Ten-eleven translocation 2 demethylates the MMP9 promoter, and its down-regulation in preeclampsia impairs trophoblast migration and invasion

Preeclampsia is the most common clinical disorder in pregnancy and might result from disordered uterine environments caused by epigenetic modifications, including deregulation of DNA methylation/demethylation. Recent research has indicated that 5-hydroxymethylcytosine (5hmC), a DNA base derived from...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Li, Xiaoliang, Wu, Chunlian, Shen, Ying, Wang, Ke, Tang, Li, Zhou, Mi, Yang, Ming, Pan, Tianying, Liu, Xinghui, Xu, Wenming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028950/
https://ncbi.nlm.nih.gov/pubmed/29773648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001265
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