Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter

Increasing evidence indicates that active DNA demethylation is involved in several processes in mammals, resulting in developmental stage-specificity and cell lineage-specificity. The recently discovered Ten-Eleven Translocation (TET) dioxygenases are accepted to be involved in DNA demethylation by...

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Autores principales: Chen, Hui, Kazemier, Hinke G, de Groote, Marloes L., Ruiters, Marcel H. J., Xu, Guo-Liang, Rots, Marianne G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919596/
https://ncbi.nlm.nih.gov/pubmed/24194590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1019
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