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Centrosome amplification disrupts renal development and causes cystogenesis
Centrosome number is tightly controlled to ensure proper ciliogenesis, mitotic spindle assembly, and cellular homeostasis. Centrosome amplification (the formation of excess centrosomes) has been noted in renal cells of patients and animal models of various types of cystic kidney disease. Whether thi...
Gorde:
| Argitaratua izan da: | J Cell Biol |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Rockefeller University Press
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028550/ https://ncbi.nlm.nih.gov/pubmed/29895697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201710019 |
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