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Centrosome amplification disrupts renal development and causes cystogenesis
Centrosome number is tightly controlled to ensure proper ciliogenesis, mitotic spindle assembly, and cellular homeostasis. Centrosome amplification (the formation of excess centrosomes) has been noted in renal cells of patients and animal models of various types of cystic kidney disease. Whether thi...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028550/ https://ncbi.nlm.nih.gov/pubmed/29895697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201710019 |
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