Xpo7 is a broad-spectrum exportin and a nuclear import receptor

Exportins bind cargo molecules in a RanGTP-dependent manner inside nuclei and transport them through nuclear pores to the cytoplasm. CRM1/Xpo1 is the best-characterized exportin because specific inhibitors such as leptomycin B allow straightforward cargo validations in vivo. The analysis of other ex...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Aksu, Metin, Pleiner, Tino, Karaca, Samir, Kappert, Christin, Dehne, Heinz-Jürgen, Seibel, Katharina, Urlaub, Henning, Bohnsack, Markus T., Görlich, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028547/
https://ncbi.nlm.nih.gov/pubmed/29748336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712013
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