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Xpo7 is a broad-spectrum exportin and a nuclear import receptor
Exportins bind cargo molecules in a RanGTP-dependent manner inside nuclei and transport them through nuclear pores to the cytoplasm. CRM1/Xpo1 is the best-characterized exportin because specific inhibitors such as leptomycin B allow straightforward cargo validations in vivo. The analysis of other ex...
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| 發表在: | J Cell Biol |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Rockefeller University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028547/ https://ncbi.nlm.nih.gov/pubmed/29748336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712013 |
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