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Trim33 mediates the proinflammatory function of Th17 cells

Transforming growth factor–β (TGF-β) regulates reciprocal regulatory T cell (T reg) and T helper 17 (Th17) differentiation, the underlying mechanism of which is still not understood. Here, we report that tripartite motif-containing 33 (Trim33), a modulator of TGF-β signaling that associates with Sma...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Tanaka, Shinya, Jiang, Yu, Martinez, Gustavo J., Tanaka, Kentaro, Yan, Xiaowei, Kurosaki, Tomohiro, Kaartinen, Vesa, Feng, Xin-Hua, Tian, Qiang, Wang, Xiaohu, Dong, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028517/
https://ncbi.nlm.nih.gov/pubmed/29930104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170779
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