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TRIMming TGF-β signals in Th17 cells

The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile.

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Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Rapaport, Aaron S., Ouyang, Wenjun
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028513/
https://ncbi.nlm.nih.gov/pubmed/29945999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180986
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