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The Roles of MDM2 and MDMX in Cancer
For more than 25 years, MDM2 and its homolog MDMX (also known as MDM4) have been shown to exert oncogenic activity. These two proteins are best understood as negative regulators of the p53 tumor suppressor, although they may have additional p53-independent roles. Understanding the dysregulation of M...
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| Foilsithe in: | Annu Rev Pathol |
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| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028239/ https://ncbi.nlm.nih.gov/pubmed/27022975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012414-040349 |
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