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Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these...

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Pubblicato in:PLoS Genet
Autori principali: Burns, Michael B., Montassier, Emmanuel, Abrahante, Juan, Priya, Sambhawa, Niccum, David E., Khoruts, Alexander, Starr, Timothy K., Knights, Dan, Blekhman, Ran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028121/
https://ncbi.nlm.nih.gov/pubmed/29924794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007376
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