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Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Burns, Michael B., Montassier, Emmanuel, Abrahante, Juan, Priya, Sambhawa, Niccum, David E., Khoruts, Alexander, Starr, Timothy K., Knights, Dan, Blekhman, Ran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028121/
https://ncbi.nlm.nih.gov/pubmed/29924794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007376
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