Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these...

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Vydáno v:PLoS Genet
Hlavní autoři: Burns, Michael B., Montassier, Emmanuel, Abrahante, Juan, Priya, Sambhawa, Niccum, David E., Khoruts, Alexander, Starr, Timothy K., Knights, Dan, Blekhman, Ran
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028121/
https://ncbi.nlm.nih.gov/pubmed/29924794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007376
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