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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release
Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4(+) T cells as part of the immune system’s surveillance of pathogens and malignancy. In the absence of peptide, MHC-II equilibrates between peptide-receptive and peptide-averse conformation...
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Publicado no: | PLoS One |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028098/ https://ncbi.nlm.nih.gov/pubmed/29965980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199704 |
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