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Interleukin (IL)-12 and IL-23 and Their Conflicting Roles in Cancer

The balance of proinflammatory cytokines interleukin (IL)-12 and IL-23 plays a key role in shaping the development of antitumor or protumor immunity. In this review, we discuss the role IL-12 and IL-23 plays in tumor biology from preclinical and clinical data. In particular, we discuss the mechanism...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Biol
Main Authors: Yan, Juming, Smyth, Mark J., Teng, Michele W.L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028064/
https://ncbi.nlm.nih.gov/pubmed/28716888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a028530
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