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Development of arrayed colonic organoids for screening of secretagogues associated with enterotoxins

Enterotoxins increase intestinal fluid secretion through the modulation of ion channels as well as activating the enteric nervous and immune systems. Colonic organoids, also known as colonoids, are functionally and phenotypically similar to in vivo colonic epithelium, and have been used to study int...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Gunasekara, Dulan B., DiSalvo, Matthew, Wang, Yuli, Nguyen, Daniel L., Reed, Mark I., Speer, Jennifer, Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028038/
https://ncbi.nlm.nih.gov/pubmed/29281259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04032
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