Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats

GPR139 is an orphan G protein-coupled receptor (GPCR) that is expressed mainly in the brain, with the highest expression in the medial habenula. The modulation of GPR139 receptor function has been hypothesized to be beneficial in the treatment of some mental disorders, but behavioral studies have no...

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Detaylı Bibliyografya
Yayımlandı:eNeuro
Asıl Yazarlar: Kononoff, Jenni, Kallupi, Marsida, Kimbrough, Adam, Conlisk, Dana, de Guglielmo, Giordano, George, Olivier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2018
Konular:
New Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027959/
https://ncbi.nlm.nih.gov/pubmed/29971251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0153-18.2018
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