Sphingolipid changes do not underlie fatty acid-evoked GLUT4 insulin resistance nor inflammation signals in muscle cells

Ceramides contribute to obesity-linked insulin resistance and inflammation in vivo, but whether this is a cell-autonomous phenomenon is debated, particularly in muscle, which dictates whole-body glucose uptake. We comprehensively analyzed lipid species produced in response to fatty acids and examine...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Pillon, Nicolas J., Frendo-Cumbo, Scott, Jacobson, Maya R., Liu, Zhi, Milligan, Paul L., Hoang Bui, Hai, Zierath, Juleen R., Bilan, Philip J., Brozinick, Joseph T., Klip, Amira
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027910/
https://ncbi.nlm.nih.gov/pubmed/29794037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M080788
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