Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of extra fat in liver cells not caused by alcohol. Elevated transaminase levels are common indicators of liver disease, including NAFLD. Previously, we demonstrated that PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), and GC...

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Udgivet i:Exp Mol Pathol
Main Authors: Larrieta-Carrasco, Elena, Flores, Yvonne N, Macias-Kauffer, Luis R, Ramírez, Paula, Quiterio, Manuel, Ramirez-Salazar, Eric G, León-Mimila, Paola, Rivera-Paredez, Berenice, Cabrera-Álvarez, Guillermo, Canizales-Quinteros, Samuel, Zhang, Zuo-Feng, López-Pérez, Tania V, Salmerón, Jorge, Velázquez-Cruz, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027652/
https://ncbi.nlm.nih.gov/pubmed/29307798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2018.01.001
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