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Bioengineering of a Full-Thickness Skin Equivalent in a 96-Well Insert Format for Substance Permeation Studies and Organ-On-A-Chip Applications

The human skin is involved in protecting the inner body from constant exposure to outer environmental stimuli. There is an evident need to screen for toxicity and the efficacy of drugs and cosmetics applied to the skin. To date, animal studies are still the standard method for substance testing, alt...

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Bibliographic Details
Published in:Bioengineering (Basel)
Main Authors: Schimek, Katharina, Hsu, Hao-Hsiang, Boehme, Moritz, Kornet, Jacob Jan, Marx, Uwe, Lauster, Roland, Pörtner, Ralf, Lindner, Gerd
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027510/
https://ncbi.nlm.nih.gov/pubmed/29880746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering5020043
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