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Insights into Membrane Translocation of Protegrin Antimicrobial Peptides by Multistep Molecular Dynamics Simulations
[Image: see text] Protegrin-1 (PG-1) is a cationic arginine-rich antimicrobial peptide. It is widely accepted that PG-1 induces membrane disruption by forming pores that lead to cell death. However, the insertion mechanism for these highly cationic peptides into the hydrophobic membrane environment...
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| Udgivet i: | ACS Omega |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2018
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026836/ https://ncbi.nlm.nih.gov/pubmed/29978143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00483 |
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