The HIV-1 Tat Protein Enhances Splicing at the Major Splice Donor Site

Transcription of the HIV-1 proviral DNA and subsequent processing of the primary transcript results in the production of a large set of unspliced and differentially spliced viral RNAs. The major splice donor site (5′ss) that is located in the untranslated leader of the HIV-1 transcript is used for t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mueller, Nancy, Pasternak, Alexander O., Klaver, Bep, Cornelissen, Marion, Berkhout, Ben, Das, Atze T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026763/
https://ncbi.nlm.nih.gov/pubmed/29743356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01855-17
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