Dengue Virus Induces Increased Activity of the Complement Alternative Pathway in Infected Cells

Severe dengue virus (DENV) infection is associated with overactivity of the complement alternative pathway (AP) in patient studies. Here, the molecular changes in components of the AP during DENV infection in vitro were investigated. mRNA for factor H (FH), a major negative regulator of the AP, was...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Cabezas, Sheila, Bracho, Gustavo, Aloia, Amanda L., Adamson, Penelope J., Bonder, Claudine S., Smith, Justine R., Gordon, David L., Carr, Jillian M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2018
Θέματα:
Pathogenesis and Immunity
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026742/
https://ncbi.nlm.nih.gov/pubmed/29743365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00633-18
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