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Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex
The Us11 protein of herpes simplex virus 1 (HSV-1) is an accessory factor with multiple functions. In virus-infected cells, it inhibits double-stranded RNA-dependent protein kinase (PKR), 2′,5′-oligoadenylate synthetase, RIG-I, and MDA-5. However, its precise role is incompletely defined. By screeni...
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| 出版年: | J Virol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026733/ https://ncbi.nlm.nih.gov/pubmed/29743370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00402-18 |
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