The Herpes Simplex Virus 1 Us11 Protein Inhibits Autophagy through Its Interaction with the Protein Kinase PKR

Autophagy is now known to be an essential component of host innate and adaptive immunity. Several herpesviruses have developed various strategies to evade this antiviral host defense. Herpes simplex virus 1 (HSV-1) blocks autophagy in fibroblasts and in neurons, and the ICP34.5 protein is important...

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Detalhes bibliográficos
Main Authors: Lussignol, Marion, Queval, Christophe, Bernet-Camard, Marie-Françoise, Cotte-Laffitte, Jacqueline, Beau, Isabelle, Codogno, Patrice, Esclatine, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554085/
https://ncbi.nlm.nih.gov/pubmed/23115300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01158-12
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