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Inhibition of Sarco-Endoplasmic Reticulum Ca(2+) ATPase Extends the Lifespan in C. elegans Worms
The sarco-endoplasmic reticulum Ca(2+)-ATPase (SERCA) refills the endoplasmic reticulum (ER) with Ca(2+) up to the millimolar range and is therefore the main controller of the ER [Ca(2+)] level ([Ca(2+)](ER)), which has a key role in the modulation of cytosolic Ca(2+) signaling and ER-mitochondria C...
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| Udgivet i: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026643/ https://ncbi.nlm.nih.gov/pubmed/29988547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00669 |
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