Systemically Administered Sindbis Virus in Combination with Immune Checkpoint Blockade Induces Curative Anti-tumor Immunity

Oncolytic viruses represent a promising form of cancer immunotherapy. We investigated the potential of Sindbis virus (SV) for the treatment of solid tumors expressing the human cancer testis antigen NYESO-1. NYESO-1 is an immunogenic antigen frequently expressed in numerous cancers, such as ovarian...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Oncolytics
Autori principali: Scherwitzl, Iris, Hurtado, Alicia, Pierce, Carolyn M., Vogt, Sandra, Pampeno, Christine, Meruelo, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026467/
https://ncbi.nlm.nih.gov/pubmed/29988525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.04.004
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