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Sindbis Virus Platform Provides an Oncolytic-Virus-Mediated and Immunotherapeutic Strategy to Overcome the Challenging Microenvironment of Pancreatic Cancer

<b>Background/Objectives:</b> Our laboratory has been developing a Sindbis viral (SV) vector platform for treatments of several types of cancers. In this study, we assess treatment efficacy for metastatic and immunosuppressive pancreatic cancer. <b>Methods:</b> Orthotopic mouse models were generated...

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Bibliografske podrobnosti
Principais autores: Silvana Opp, Christine Pampeno, Alicia Hurtado, Daniel Meruelo
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2025-05-01
Serija:Pharmaceuticals
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Online dostop:https://www.mdpi.com/1424-8247/18/5/725
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