Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/ choroid in chick model of form-deprivation myopia

PURPOSE: RNA sequencing analysis has demonstrated bidirectional changes in metabolism, structural and immune pathways during early induction of defocus induced myopia. Thus, the aim of this study was to investigate whether similar gene pathways are also related to the more excessive axial growth, ul...

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Pubblicato in:PeerJ
Autori principali: Giummarra, Loretta, Crewther, Sheila G., Riddell, Nina, Murphy, Melanie J., Crewther, David P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2018
Soggetti:
Bioinformatics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026464/
https://ncbi.nlm.nih.gov/pubmed/29967729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5048
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