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Age-dependent alpha-synuclein accumulation and aggregation in the colon of a transgenic mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is one of the most common neurodegenerative diseases, neuropathologically characterized by misfolded protein aggregation, called Lewy bodies and Lewy neurites. PD is a slow-progressive disease with colonic dysfunction appearing in the prodromal stage and lasting...

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Dettagli Bibliografici
Pubblicato in:Transl Neurodegener
Autori principali: Chen, Qian-Qian, Haikal, Caroline, Li, Wen, Li, Ming-Tao, Wang, Zhan-You, Li, Jia-Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026335/
https://ncbi.nlm.nih.gov/pubmed/29988485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-018-0118-8
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