Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet

OBJECTIVES: Glycemic control by medical treatment represents one therapeutic strategy for diabetic patients. The Na+-d-glucose cotransporter 1 (SGLT1) is currently of high interest in this context. SGLT1 is known to mediate glucose absorption and incretin secretion in the small intestine. Recently,...

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Publicat a:Mol Metab
Autors principals: Mühlemann, Markus, Zdzieblo, Daniela, Friedrich, Alexandra, Berger, Constantin, Otto, Christoph, Walles, Heike, Koepsell, Hermann, Metzger, Marco
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026318/
https://ncbi.nlm.nih.gov/pubmed/29859847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.05.011
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