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Amino acid-level signal-to-noise analysis of incidentally identified variants in genes associated with long QT syndrome during pediatric whole exome sequencing reflects background genetic noise
BACKGROUND: Due to rapid expansion of clinical genetic testing, an increasing number of genetic variants of undetermined significance are being identified in children with unclear diagnostic value. Variants found in genes associated with heritable channelopathies, such as long QT syndrome (LQTS), ar...
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出版年: | Heart Rhythm |
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主要な著者: | , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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2018
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026069/ https://ncbi.nlm.nih.gov/pubmed/29501670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2018.02.031 |
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