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JAK inhibitors in autoinflammation

Interferonopathies are a subset of autoinflammatory disorders with a prominent type I IFN gene signature. Treatment of these patients has been challenging, given the lack of response to common autoinflammatory therapeutics including IL-1 and TNF blockade. JAK inhibitors (Jakinibs) are a family of sm...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Hoffman, Hal M., Broderick, Lori
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025991/
https://ncbi.nlm.nih.gov/pubmed/29889100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121526
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