Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β

Ischemia-reperfusion injury, a form of sterile inflammation, is the leading risk factor for both short-term mortality following pulmonary transplantation and chronic lung allograft dysfunction. While it is well recognized that neutrophils are critical mediators of acute lung injury, processes that g...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hsiao, Hsi-Min, Fernandez, Ramiro, Tanaka, Satona, Li, Wenjun, Spahn, Jessica H., Chiu, Stephen, Akbarpour, Mahzad, Ruiz-Perez, Daniel, Wu, Qiang, Turam, Cem, Scozzi, Davide, Takahashi, Tsuyoshi, Luehmann, Hannah P., Puri, Varun, Budinger, G.R. Scott, Krupnick, Alexander S., Misharin, Alexander V., Lavine, Kory J., Liu, Yongjian, Gelman, Andrew E., Bharat, Ankit, Kreisel, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025976/
https://ncbi.nlm.nih.gov/pubmed/29781811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98436
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