Heart-resident CCR2(+) macrophages promote neutrophil extravasation through TLR9/MyD88/CXCL5 signaling

It is well established that maladaptive innate immune responses to sterile tissue injury represent a fundamental mechanism of disease pathogenesis. In the context of cardiac ischemia reperfusion injury, neutrophils enter inflamed heart tissue, where they play an important role in potentiating tissue...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Li, Wenjun, Hsiao, Hsi-Min, Higashikubo, Ryuji, Saunders, Brian T., Bharat, Ankit, Goldstein, Daniel R., Krupnick, Alexander S., Gelman, Andrew E., Lavine, Kory J., Kreisel, Daniel
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985028/
https://ncbi.nlm.nih.gov/pubmed/27536731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87315
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