Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

Neurofibromatosis type 1 associates with multiple neoplasms, and the Schwann cell tumor neurofibroma is the most prevalent. A hallmark feature of neurofibroma is mast cell infiltration, which is recruited by chemoattractant stem cell factor (SCF) and has been suggested to sustain neurofibroma tumori...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Liao, Chung-Ping, Booker, Reid C., Brosseau, Jean-Philippe, Chen, Zhiguo, Mo, Juan, Tchegnon, Edem, Wang, Yong, Clapp, D. Wade, Le, Lu Q.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025974/
https://ncbi.nlm.nih.gov/pubmed/29596064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99424
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