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Conformational Plasticity in the Selectivity Filter of the TRPV2 Ion Channel

Transient receptor potential vanilloid (TRPV) channels are activated by ligands and heat, and are involved in various physiological processes. In contrast to the architecturally-related voltage-gated cation channels, TRPV1 and TRPV2 subtypes possess another activation gate at the selectivity filter...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Zubcevic, Lejla, Le, Son, Yang, Huanghe, Lee, Seok-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025827/
https://ncbi.nlm.nih.gov/pubmed/29728656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0059-z
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