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Modulating the serotonin receptor spectrum of pulicatin natural products

Serotonin (5-HT) receptors are important in health and disease, but the existence of 14 subtypes necessitates selective ligands. Previously, the pulicatins were identified as ligands that specifically bound to the subtype 5-HT2B in the 500 nM-10 μM range and that exhibited in vitro effects on cultur...

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Detalles Bibliográficos
Publicado en:J Nat Prod
Main Authors: Lin, Zhenjian, Smith, Misty D., Concepcion, Gisela P., Haygood, Margo G., Olivera, Baldomero M., Light, Alan, Schmidt, Eric W.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025773/
https://ncbi.nlm.nih.gov/pubmed/28745513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.7b00317
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