Griseorhodins D–F, Neuroactive Intermediates and End Products of Post-PKS Tailoring Modification in Griseorhodin Biosynthesis

[Image: see text] The griseorhodins belong to a family of extensively modified aromatic polyketides that exhibit activities such as inhibition of HIV reverse transcriptase and human telomerase. The vast structural diversity of this group of polyketides is largely introduced by enzymatic oxidations,...

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Detalhes bibliográficos
Main Authors: Lin, Zhenjian, Zachariah, Malcolm M., Marett, Lenny, Hughen, Ronald W., Teichert, Russell W., Concepcion, Gisela P., Haygood, Margo G., Olivera, Baldomero M., Light, Alan R., Schmidt, Eric W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039362/
https://ncbi.nlm.nih.gov/pubmed/24786728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500155d
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