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The mTOR Pathway Regulates PKM2 to Affect Glycolysis in Esophageal Squamous Cell Carcinoma

OBJECTIVES: Esophageal squamous cell carcinoma is a highly prevalent cancer withpoor survival rate and prognosis. Increasing evidence suggests an important role for metabolic regulation in treating esophageal squamous cell carcinoma, but the underlying mechanism remains unclear. The pyruvate kinase...

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Bibliografiske detaljer
Udgivet i:Technol Cancer Res Treat
Main Authors: Xiaoyu, He, Yiru, Yin, Shuisheng, Shi, Keyan, Cheng, Zixing, Yan, Shanglin, Cheng, Yuan, Wang, Dongming, Cheng, Wangliang, Zhang, Xudong, Bai, Jie, Ma
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024499/
https://ncbi.nlm.nih.gov/pubmed/29916308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1533033818780063
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