Clinicopathological and prognostic significance of mTOR and phosphorylated mTOR expression in patients with esophageal squamous cell carcinoma: a systematic review and meta-analysis

BACKGROUND: Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase responsible for regulating ribosomal biogenesis and protein synthesis. Dysregulation of mTOR contributes to tumorigenesis, angiogenesis, cellular growth and metastasis but its roles in esophageal squamous cell carc...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Li, Shuangjiang, Wang, Zhiqiang, Huang, Jian, Cheng, Shan, Du, Heng, Che, Guowei, Peng, Yong
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106813/
https://ncbi.nlm.nih.gov/pubmed/27835987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2940-7
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