Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice

Acetaminophen overdose is the most common cause of acute liver injury (ALI) or acute liver failure in the United States. Its pathogenetic mechanisms are incompletely understood. Additional studies are warranted to identify new genetic risk factors for more mechanistic insights and new therapeutic ta...

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Pubblicato in:Am J Pathol
Autori principali: Zhang, Li Q., Nsumu, Marianne, Huang, Peixin, Heruth, Daniel P., Riordan, Sean M., Shortt, Katherine, Zhang, Nini, Grigoryev, Dmitry N., Li, Ding-You, Friesen, Craig A., Van Haandel, Leon, Leeder, J. Steven, Olson, Jody, Ye, Shui Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024191/
https://ncbi.nlm.nih.gov/pubmed/29684358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.04.004
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