Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice

Acetaminophen overdose is the most common cause of acute liver injury (ALI) or acute liver failure in the United States. Its pathogenetic mechanisms are incompletely understood. Additional studies are warranted to identify new genetic risk factors for more mechanistic insights and new therapeutic ta...

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Vydáno v:Am J Pathol
Hlavní autoři: Zhang, Li Q., Nsumu, Marianne, Huang, Peixin, Heruth, Daniel P., Riordan, Sean M., Shortt, Katherine, Zhang, Nini, Grigoryev, Dmitry N., Li, Ding-You, Friesen, Craig A., Van Haandel, Leon, Leeder, J. Steven, Olson, Jody, Ye, Shui Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024191/
https://ncbi.nlm.nih.gov/pubmed/29684358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.04.004
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