FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells

A major challenge in single-molecule imaging is tracking the dynamics of proteins or complexes for long periods of time in the dense environments found in living cells. Here, we introduce the concept of using FRET to enhance the photophysical properties of photo-modulatable (PM) fluorophores commonl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Basu, Srinjan, Needham, Lisa-Maria, Lando, David, Taylor, Edward J. R., Wohlfahrt, Kai J., Shah, Devina, Boucher, Wayne, Tan, Yi Lei, Bates, Lawrence E., Tkachenko, Olga, Cramard, Julie, Lagerholm, B. Christoffer, Eggeling, Christian, Hendrich, Brian, Klenerman, Dave, Lee, Steven F., Laue, Ernest D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023872/
https://ncbi.nlm.nih.gov/pubmed/29955052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04486-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados