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Calculation of 3D genome structures for comparison of chromosome conformation capture experiments with microscopy: An evaluation of single-cell Hi-C protocols

Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell variability in the organization and packaging of genomes. These single-cell methods, unlike their multi-cell counterparts, allow straightforward computation of realistic chromosome conformations that may...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Lando, David, Stevens, Tim J., Basu, Srinjan, Laue, Ernest D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883084/
https://ncbi.nlm.nih.gov/pubmed/29431585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2018.1438799
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