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Single cell Hi-C reveals cell-to-cell variability in chromosome structure
Large-scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and DNA replication and repair. Genomic techniques based on chromosome conformation capture assess contacts for millions of loci simultaneously, but do so by averaging chromosome conformat...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869051/ https://ncbi.nlm.nih.gov/pubmed/24067610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12593 |
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