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Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response

The omnipresence of allosteric regulation together with the fundamental role of structural dynamics in this phenomenon have initiated a great interest to the detection of regulatory exosites and design of corresponding effectors. However, despite a general consensus on the key role of dynamics most...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Tee, Wei-Ven, Guarnera, Enrico, Berezovsky, Igor N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023240/
https://ncbi.nlm.nih.gov/pubmed/29912863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006228
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