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Structural modification of the tripeptide KPV by reductive “glycoalkylation” of the lysine residue

Peptides that exhibit enzymatic or hormonal activities are regulatory factors and desirable therapeutic drugs because of their high target specificity and minimal side effects. Unfortunately, these drugs are susceptible to enzymatic degradation, leading to their rapid elimination and thereby demandi...

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Опубликовано в: :PLoS One
Главные авторы: Songok, Abigael C., Panta, Pradip, Doerrler, William T., Macnaughtan, Megan A., Taylor, Carol M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023233/
https://ncbi.nlm.nih.gov/pubmed/29953505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199686
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