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Structural modification of the tripeptide KPV by reductive “glycoalkylation” of the lysine residue

Peptides that exhibit enzymatic or hormonal activities are regulatory factors and desirable therapeutic drugs because of their high target specificity and minimal side effects. Unfortunately, these drugs are susceptible to enzymatic degradation, leading to their rapid elimination and thereby demandi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Songok, Abigael C., Panta, Pradip, Doerrler, William T., Macnaughtan, Megan A., Taylor, Carol M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023233/
https://ncbi.nlm.nih.gov/pubmed/29953505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199686
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