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Uncovering the fine print of the CreER(T2)-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene

FAcilitates Chromatin Transcription (FACT) is a complex of SSRP1 and SPT16 that is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT has been mostly studied in cell-free or single cell model systems because general FACT knockout (KO) is embryonically lethal (E3...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sandlesh, Poorva, Juang, Thierry, Safina, Alfiya, Higgins, Michael J., Gurova, Katerina V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023160/
https://ncbi.nlm.nih.gov/pubmed/29953487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199785
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