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Dysfunctional Nav1.5 channels due to SCN5A mutations
The voltage-gated sodium channel 1.5 (Nav1.5), encoded by the SCN5A gene, is responsible for the rising phase of the action potential of cardiomyocytes. The sodium current mediated by Nav1.5 consists of peak and late components (I(Na-P) and I(Na-L)). Mutant Nav1.5 causes alterations in the peak and...
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| Publicado no: | Exp Biol Med (Maywood) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022915/ https://ncbi.nlm.nih.gov/pubmed/29806494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370218777972 |
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