Inhibiting tumor necrosis factor‐alpha at time of induced intervertebral disc injury limits long‐term pain and degeneration in a rat model

BACKGROUND: Painful intervertebral disc (IVD) degeneration has tremendous societal costs and few effective therapies. Intradiscal tumor necrosis factor‐alpha (TNFα) is commonly associated with low back pain, but the direct relationship remains unclear. PURPOSE: Treatment strategies for low back pain...

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Detalhes bibliográficos
Publicado no:JOR Spine
Main Authors: Evashwick‐Rogler, Thomas W., Lai, Alon, Watanabe, Hironobu, Salandra, Jonathan M., Winkelstein, Beth A., Cho, Samuel K., Hecht, Andrew C., Iatridis, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022768/
https://ncbi.nlm.nih.gov/pubmed/29963655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1014
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