Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo

BACKGROUND CONTEXT: Painful intervertebral disc degeneration is extremely common and costly. Effective treatments are lacking because the nature of discogenic pain is complex with limited capacity to distinguish painful conditions from age-related changes in the spine. Hypothesized sources of discog...

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Veröffentlicht in:Spine J
Hauptverfasser: Lai, Alon, Moon, Andrew, Purmessur, Devina, Skovrlj, Branko, Laudier, Damien M., Winkelstein, Beth A., Cho, Samuel K., Hecht, Andrew C., Iatridis, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913353/
https://ncbi.nlm.nih.gov/pubmed/26610672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2015.11.019
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